Thermochemical Continuous Batch EDS

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Thermochemical EDS

The Bio-Response Thermochemical EDS is the perfect alternative for any Level 1-4 facility when the High Temperature EDS is out of budget. Aside from its lower initial cost, it has a wonderful advantage in that it can still function in the event of a steam utility failure. If you lose your steam supply, the system can keep your lab up and running with chemical-only cycles. On the other hand, it can also operate as a thermal-only system at up to 200 degrees F (93 degrees C) with an extended "exposure period" to ensure that full kill is achieved. This is an extremely versatile system that can adapt to your facility needs, and delivers performance and value that our competition can not touch.


EDS Product Brochure Bio-Response Solutions Effluent Decontamination Systems
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Thermochemical Continuous Batch Pros/Cons

Advantages (Pros) Operates up to 93°C / 200°F with or without chemical catalyst
Medium cost system, medium cost of operation
Can operate on temperature alone, chemical alone, or temperature and chemical. Perfect in the event that heating utilities are lost.
Uses less cooling energy (water or chilled water), possible to use no cooling energy
Operates at ambient pressure
Can be heated by electric immersion coils or steam coil
Fully ethernet integrated controls are a standard feature
Suitable for all biosafety levels (1-4), can treat pathogenic spores (species, contact, and temperature dependent)
Can be used with several chemicals to best suite your application
May be heated by live steam injection
One collector, two cooker systems can be fitted with an 85% energy recovery skid
Disadvantages (Cons) Cannot be used with NaOCl due to stainless process tank, but can be used with a sterilant (ClO2)
Longer soak time with temperature process alone
Does not achieve recognized "sterilization" temperature of 121°C / 250°F, however, Bio-Response can help you with the proper exposure times to inactivate specific agents
General Discussion This lower cost, lower energy approach combines known thermal levels to destroy all level 3 and 4 agents with temperature alone, and the capability to operate with a chemical to catalyze the process. It can be used with KOH or NaOH to dissolve tissue and fats. It can also be electrically heated with immersion heaters or steam heated by a steam coil or live steam injection. If a problem exists with the steam supply, the operator can bump up chemical levels to continue processing as a chemical-only system, and can achieve sterilization using chlorine dioxide (the recommended chemical). This is a good compromise between system cost and system performance.



Approximate time required to inactivate microorganisms by thermal treatment*
Microorgamism 200 degrees F
93 degrees C
200 degrees F
93 degrees C with Peroxide
212 degrees F
100 degrees C
250 degrees F
121 degrees C
Geobacillus stearothermophilus
> 10 hours
< 1 hour
~ 10 hours
< 15 min
Bacillus atrophaeus
< 45 min
< 45 min
< 30 min
< 1 min
Bacillus anthracis
< 45 min
< 45 min
< 30 min
< 1 min
All vegetative bacterial, fungal, and viral pathogens
< 15 min
< 15 min
< 10 min
< 30 seconds
*Assumes wet heat, as exists in an EDS cooker (dry heat requires dramatically longer times).
*10 log 6 reduction is the standard of reduction for this chart.
The highlighted green section indicates the thermal operating parameters of the Bio-Response Thermo-Chemical EDS.
The highlighted blue section indicates initial testing results using thermal treatment with a hydrogen peroxide catalyst. Test data to be available in late October.



Bio-Response Unique Features

Liquiphant Piezoelectric Level Sensors Redundant Liquiphant level sensors eliminate troublesome load cells, unsafe associated flexible drain connection lines, and unreliable radar or sonar level sensing devices.
Internal Heating Coils Faster heating and drastically increases vessel life.
Welded Stainless Steel Skins Insulation is completely sealed and safe. We have the safest, most attractive, and highest quality vessels in the EDS industry.
Internal Solids Basket Collects and treats solids so that you never have a safety hazzard or drain problems (optional on Thermochemical EDS)
Automated Cooling Treated hot effluent is cooled in a quiet and energy efficient manner.
No short stubs Our short, large diameter stubs leave allow sterilization temperatures to reach mounted devices.  There are no cold spots; safe and complete processing occurs in a Bio-Response EDS every cycle.
GE Fanuc Controls State-of-the-art touch screen with Ethernet connectivity. This is the most technologically advanced and versatile system available and it is standard on all Bio-Response systems. (Optional Allen Bradley and others).
Automated Chemical Injection The Bio-Response chemical injection system is completely automated and measures a precise amount of chemical for each cycle. Chemical concentration is easily user adjustable from the touch screen.


BELOW: This Thermo-Chemical EDS is compact and is designed to fit into a tight space. It utilizes our fast heating internal steam coils and all components are easily accessible for monitoring and maintenance. There are systems on the market that are not only extremely difficult to service, but they are dangerous to service. This system is also expandable and is shown below in its 100 gallon redundant cooker configuration (two 50 gallon cookers). Treatment is achieved by thermal reaction in a 60 minute cook cycle (user adjustable for more cook time), but it also features an automated chemical injection system for true Thermo-Chemical process results.

Small thermochemical EDS














BELOW: A Low Temperature Continuous Batch system that was designed for Agrobacterium. It heats to full temperature ( 93°C / 200°F) in 15 minutes thanks to our internal steam coil and offers a rapid turnaround time for maximum production.











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